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Fig. 2. Peiminine ameliorated myocardial infarction-induced tissues damage in rats. (A) Influence of left coronary artery ligation and peiminine administration on cardiomyocyte disturbances, inflammatory infiltration and structure of heart tissues detected by Hematoxylin-Eosin staining (×200). (B) Peiminine administration reduced myocardial infarction-induced increase of infarct size in rats detected by TTC staining. (C) Peiminine administration inhibited the myocardial infarction-induced increase of lactate dehydrogenase (LDH) in rats detected by ELISA. Peiminine administration inhibited the myocardial infarction-induced increase of creatine kinase-MB (CK-MB) in rats detected by ELISA. ** vs. sham, p < 0.01. ## vs. myocardial infarction (MI), p < 0.01.
Korean J Physiol Pharmacol 2022;26:87-94 https://doi.org/10.4196/kjpp.2022.26.2.87
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