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Fig. 4. Lithium chloride inhibits the expression of AMPH-induced conditioned locomotor activity. All rats were tested following an IP saline or lithium chloride (50 mg/kg) injection. Data are shown as group mean + SEM total locomotor activity counts observed during the 1 h test. Symbols indicate significant differences revealed by post-hoc Bonferroni comparison following two-way ANOVA. ***p < 0.001, significantly more counts in the Paired rats relative to those in the Control and Unpaired groups. †††p < 0.001, significantly different from no lithium treated the Paired group. Time-course data is shown in the inset as group mean + SEM locomotor activity counts at 20 min intervals. Numbers for each group are 8. AMPH, amphetamine; IP, intraperitoneal; CTL, control; LiCl, lithium chloride.
Korean J Physiol Pharmacol 2022;26:59-65
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