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Fig. 3. The effects of the specific NAMPT inhibitor, FK866, on mineralization in MDPC-23 cells. (A) MDPC-23 cell viability after FK866 treatment as determined by MTT assays. (B) Alizarin Red S stain (left panel) showing mineralized nodule formation in MDPC-23 cells, cultured in differentiation media and treated with FK866 for up to 10 days. The mineralization was quantified using colorimetric spectrophotometry (right panel). Each data point represents the mean ± SEM of three experiments. NAMPT, nicotinamide phosphoribosyltransferase; MDPC-23, mouse dental papilla cell-23. *p < 0.05, **p < 0.01, ***p < 0.001.
Korean J Physiol Pharmacol 2022;26:37-45
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