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Fig. 2. Effects of vehicle and antagonists on isometric contractions of mouse vas deferens produced by 10 pulses at 1 Hz, expressed as % of control. The effects of (A) vehicle (veh) (4 additions), (B) BMY7378 (BMY) (10 nM–10 µM), (C) RS100329 (1 nM–1 µM) and (D) prazosin (praz) (1 nM–1 µM) on isometric contractions to each pulse of 10 pulse field stimulation at 1 Hz in mouse vas deferens, expressed as % of control response (see for responses expressed as absolute tension). Values are presented as mean ± SEM from 6 experiments. Responses in the presence of antagonist were compared with the effects of respective vehicle by 2 way analysis of variance and Bonferroni post-hoc test. Asterisks denote effects of antagonist significantly different from the effects of vehicle in response to a given pulse, and are colour coded to match the antagonist concentration symbol colour: *p < 0.05; **p < 0.01; ***p < 0.001.
Korean J Physiol Pharmacol 2021;25:525-532 https://doi.org/10.4196/kjpp.2021.25.6.525
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