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Fig. 1. Effects of vehicle and antagonists on isometric contractions of mouse vas deferens produced by 10 pulses at 1 Hz, expressed as tension in grams. (A) Original recording of isometric contractions obtained to field stimulation in mouse vas deferens with 10 pulses at 1 Hz. The vertical axis shows tension in grams. The horizontal axis shows pulse number at 1 Hz and the time between each pulse is 1 sec. The response to the first pulse is clearly shown. (B–E) The effects of (B) vehicle (veh) (4 additions), (C) BMY7378 (BMY) (10 nM–10 µM), (D) RS100329 (1 nM–1 µM) and (E) prazosin (praz) (1 nM–1 µM) on isometric contractions to each pulse of 10 pulse field stimulation at 1 Hz in mouse vas deferens, expressed as absolute tension in grams. Values are presented as mean ± SEM from 6 experiments. Statistical tests were carried out on data expressed as a percentage of control (see ).
Korean J Physiol Pharmacol 2021;25:525-532
© Korean J Physiol Pharmacol