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Fig. 2. Rosavin inhibits cold stimuli‐evoked behavioral hypersensitivity in the oxaliplatin group. Rosavin (1 mg/kg, n = 7; 5 mg/kg, n = 7; 10 mg/kg, n = 8) or vehicle (control, n = 9) was administrated to randomly assigned animals. The acetone drop assay was performed four times, once before application and reassessments at 30, 60, and 120 min post-dosing, respectively (timeline: 0, 30, 60, and 120). Data are expressed as mean ± SEM; *p < 0.05, vs. vehicle; by Bonferroni post-hoc test after two-way analysis of variance (ANOVA).
Korean J Physiol Pharmacol 2021;25:489-494 https://doi.org/10.4196/kjpp.2021.25.5.489
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