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Fig. 1. Changes in cold hypersensitivity over time in oxaliplatin and control groups. Animals were randomly administered 5% glucose solution or oxaliplatin (vehicle or OXA, n = 8/group). Mice were subjected to the acetone drop test immediately before the administration on day 0 and from days 1 to 7, respectively (timeline: days 0, 1, 3, 5, and 7). The acetone-elicited responses were counted over 30 s post-applications. Data are expressed as mean ± SEM; *p < 0.05, **p < 0.01, vs. vehicle; by Bonferroni post-hoc test after two-way analysis of variance (ANOVA).
Korean J Physiol Pharmacol 2021;25:489-494
© Korean J Physiol Pharmacol