Table. 3.

Physicochemical and encapsulation characteristics of DTX-NP (n = 3)

DTX (mg) Particle size (nm) PDI Zeta potential (mV) EE (%) DL (%)
0 155.7 ± 1.7 0.19 ± 0.012 –27.3 ± 0.55
3 160.5 ± 3.0 0.21 ± 0.007 –26.7 ± 0.46 81.3 ± 1.85 10.6 ± 0.24
6 174.4 ± 0.8 0.18 ± 0.019 –29.9 ± 1.50 70.2 ± 1.60 8.09 ± 0.18
9 205.9 ± 8.2 0.23 ± 0.022 –26.9 ± 0.50 50.2 ± 2.54 5.19 ± 0.26

Values are presented as mean ± SD. DTX-NP, docetaxel loaded poly(lactic-co-glycolic acid) nanoparticle; PDI, polydispersity index; EE, encapsulation efficiency; DL, drug loading.

Korean J Physiol Pharmacol 2021;25:479-488 https://doi.org/10.4196/kjpp.2021.25.5.479
© Korean J Physiol Pharmacol