Table. 2.

Optimization percentage of PLGA in NP (n = 3)

PLGA (%) TPGS (%) Particle size (nm) PDI Zeta potential (mV)
1 1 155.7 ± 1.7 0.19 ± 0.01 –27.3 ± 0.55
2 1 311.4 ± 43 0.52 ± 0.03 –33.0 ± 1.23
3 1 268.3 ± 63 0.43 ± 0.02 –33.4 ± 2.55
5 1 307.0 ± 12 0.29 ± 0.10 –22.8 ± 0.56
7 1 256.4 ± 57 0.29 ± 0.07 –22.8 ± 0.60

Values are presented as mean ± SD. PLGA, poly(lactic-co-glycolic acid); NP, nanoparticle; TPGS, tocopherol polyethylene glycol succinate; PDI, polydispersity index.

Korean J Physiol Pharmacol 2021;25:479-488 https://doi.org/10.4196/kjpp.2021.25.5.479
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