Table. 1.

Optimization percentage of TPGS (n = 3)

PLGA (%) TPGS (%) Particle size (nm) PDI Zeta potential (mV)
1 0.05 260.3 ± 30 0.31 ± 0.03 –21.8 ± 0.20
1 0.1 202.2 ± 1.6 0.20 ± 0.02 –25.2 ± 0.67
1 0.5 204.2 ± 3.2 0.21 ± 0.02 –21.1 ± 1.27
1 1 155.7 ± 1.7 0.19 ± 0.01 –27.3 ± 0.55
1 2 204.9 ± 5.7 0.30 ± 0.05 –23.6 ± 0.93
1 3 164.4 ± 2.7 0.19 ± 0.02 –25.2 ± 1.16

Values are presented as mean ± SD. TPGS, α-tocopherol polyethylene glycol 1000 succinate; PLGA, poly(lactic-co-glycolic acid); PDI, polydispersity index.

Korean J Physiol Pharmacol 2021;25:479-488 https://doi.org/10.4196/kjpp.2021.25.5.479
© Korean J Physiol Pharmacol