Fig. 3. Cytotoxicity assay of the PAMAMG3 derivatives.
(A, B) GBL-14 cells and (C, D) human dermal fibroblasts (HDFs) were exposed to various concentrations of PAMAMG3, PAMAMG3-KRRR, and PAMAMG3-HKRRR. Cytotoxicity was assessed by WST-1 assay after 24 h (A, C) and 48 h (B, D). Values are expressed as the mean ± SD of three independent experiments (n = 3). (E, F) GBL-14 cells and (G, H) HDFs were incubated under similar condition as in WST-1 assay. Cytotoxicity was assessed using LDH assay after 24 h (E, G) and 48 h (F, H). Values are expressed as the mean ± SD of three independent experiments (n = 3).
© Korean J Physiol Pharmacol
