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Fig. 3. DH enhances EPC functional ability. (A) EPCs treated with or without DH (0.5 µM) were seeded on matrigel-coated wells and the angiogenic function was evaluated in a tube formation assay. Representative images of tube formation (40×). (B, C) Quantification of the number of branches and length. (D, E) Representative images of the scratch wound healing and migration assay. (F, G) Quantification of the migrated area and number of migrated cells. Data represent the mean ± SEM. DH, dronedarone hydrochloride; EPC, endothelial progenitor cell. The results are considered statistically significant at *p < 0.05, **p < 0.01, ***p < 0.001 when compared to untreated groups.
Korean J Physiol Pharmacol 2021;25:459-466
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