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Fig. 2. Expression levels of IL-6, IL-17, and TNF-α mRNA in small intestine after ACF-induced enteropathy. Expression of IL-6 (A), IL-17 (B), and TNF-α (C) was quantified using qRT-PCR. The relative mRNA levels of IL-6, IL-17, and TNF-α were calculated by normalizing them to the expression level of GAPDH by using the 2–∆∆Ct method. The expression values obtained from the drug-treated small intestine were normalized to those of the control. Data are represented as the mean ± SEM. A, aceclofenac (ACF); D, DA-9601; E esomeprazole. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.
Korean J Physiol Pharmacol 2021;25:439-448
© Korean J Physiol Pharmacol