Table. 1.

Basic parameters of rats in control, DM, and DM + Sitagliptin groups

Variable Controls (n = 8) DM (n = 8) DM + Sitagliptin (n = 8)
Body weight (g) 538.88 ± 50.16 424.17 ± 48.02* 380.08 ± 22.66*,#
Weight gain (g) 147.38 ± 37.53 65.50 ± 22.04* 50.33 ± 15.81*
FBG (mM) 3.55 ± 0.24 9.48 ± 2.28* 8.28 ± 2.01*
Random BG (mM) 4.76 ± 0.26 20.1 ± 2.49* 17.07 ± 1.46*,#
TC (mM) 1.00 ± 0.27 1.44 ± 0.46* 0.86 ± 0.28#
TG (mM) 0.40 ± 0.09 0.70 ± 0.49 0.68 ± 0.13*
LDL-C (mM) 0.17 ± 0.04 0.18 ± 0.05 0.11 ± 0.04*,#

Values are presented as mean ± SD. FBG, fasting blood glucose; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; DM, diabetes mellitus. *p < 0.05 vs. control group; #p < 0.05 vs. DM group.

Korean J Physiol Pharmacol 2021;25:425-437 https://doi.org/10.4196/kjpp.2021.25.5.425
© Korean J Physiol Pharmacol