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Fig. 6. Effect of N-acetyl-p-aminophenol (APAP) in the presence or absence of tissue factor (TF) deoxyoligonucleotides (ODNs) injection on the survival rate of mice. Animal survivability was analyzed in mice treated with APAP with or without TF ODNs for four days. Mice treated with APAP alone exhibit 6 out of 10 were survived at the end of the experiment. Similarly, 60% of the animals were survived after 4 days of treatment in APAP + TF-SC. On the other hand, mice treated with APAP in the presence of TF-AS showed 100% survivability (p < 0.05). MCT/LPS, monocrotaline/lipopolysaccharide.
Korean J Physiol Pharmacol 2021;25:385-393
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