Table. 1.

Effect of APAP in the presence or absence of TF ODNs (TF-SC and TF-AS) on WBCs and platelets count

Groups Parameters
WBCs (103/mm3) Platelets count (/mm3)
Control 5.33 ± 0.57 800.3 ± 44.30
APAP-treated 12.19a ± 2.34 547.3a ± 92.09
APAP + TF-SC 13.35a ± 1.96 552.3a ± 80.56
APAP + TF-AS 7.17b ± 0.655 730.3b ± 29.74

Data in the table are expressed as means ± standard deviation. APAP, N-acetyl-p-aminophenol; TF, tissue factor; ODN, deoxyoligonucleotide; WBC, white blood cells. aDifferent significantly from vehicle treated mice. bDifferent significantly from APAP + TF-SC-treated using one-way ANOVA followed by Tukey-Kramer test as post ANOVA for multiple comparison (p < 0.05).

Korean J Physiol Pharmacol 2021;25:385-393 https://doi.org/10.4196/kjpp.2021.25.5.385
© Korean J Physiol Pharmacol