Table. 2.

Effects of CARD on the serum levels of testosterone, FSH, LH, sperm number and motility in all experimental groups

Variable Testosterone (ng/ml) FSH (ng/ml) LH (ng/ml) Sperm number (×106) Sperm motility (%)
Control 4.89 ± 0.97 6.22 ± 0.64 7.21 ± 0.90 167.46 ± 6.45 13.60 ± 1.43
CARD 5.13 ± 0.83 6.60 ± 0.84 7.55 ± 0.49 171.22 ± 6.82 14.84 ± 1.42
DM 1.25 ± 0.21* 2.92 ± 0.65* 4.11 ± 0.89* 42.22 ± 8.37* 3.18 ± 0.88*
DM + GLIB 2.34 ± 0.65*,# 3.54 ± 0.64*,# 4.62 ± 0.89*,# 87.10 ± 6.33*,# 5.33 ± 0.75*,#
DM + CARD 3.02 ± 0.64*,#,$ 4.48 ± 0.63*,#,$ 5.16 ± 0.90*,#,$ 100.35 ± 7.10*,#,$ 6.88 ± 0.89*,#,$
DM + GLIB + CARD 3.85 ± 0.53#,$,@ 5.18 ± 0.87#,$,@ 6.29 ± 0.89#,$,@ 138.24 ± 8.95*,#,$,@ 10.87 ± 1.39*,#,$,@

Values are presented as mean ± SD. CARD, normal rat supplemented with cardamonin; FSH, follicle stimulating hormone; LH, luteinizing hormone; DM, untreated diabetic group; DM + GLIB, diabetic rats treated with glibenclamide; DM + CARD, diabetic rats treated with cardamonin; DM + GLIB + CARD, diabetic rats treated with both glibenclamide and cardamonin. Test used: One-way ANOVA followed by post-hoc Tukey’s test. *Represents significance compared with the control group; #represents significance compared with the DM group; $represents significance compared with the DM + GLIB group; @represents significance compared with the DM + CARD group.

Korean J Physiol Pharmacol 2021;25:341-354 https://doi.org/10.4196/kjpp.2021.25.4.341
© Korean J Physiol Pharmacol