Fig. 3. Effects of mangiferin on cardiac oxidative stress (A) and inflammation (B) in D-gal-induced aging rats.
The activities of enzymatic antioxidants SOD and CAT, as well as the level of lipid peroxidation marker MDA and proinflammatory cytokines IL-1β, IL-6 and TNF-α were measured in accordance with the instructions of commercial kits. Values (n = 8) were presented as mean ± standard deviation. D-gal, D-galactose; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde; IL, interleukin; TNF, tumor necrosis factor; Veh group, vehicle control group; Aging group, D-gal-induced aging group. **p < 0.01 compared to the Aging group. ##p < 0.01 compared to the Veh group.
© Korean J Physiol Pharmacol
