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Fig. 1. Effects of mangiferin on serum levels (A) of CK and LDH, as well as on cardiac expression (B) of ANP, BNP, and β-MHC in D-gal-induced aging rats. The levels of serum CK and LDH were detected using commercial kits according to instructions (n = 8). The expression of cardiac ANP, BNP, and β-MHC was detected by Western blot analysis (n = 3). Values were presented as mean ± standard deviation. CK, creatine kinase; LDH, lactate dehydrogenase; ANP, natriuretic peptides A; β-MHC, β-myosin heavy chain; D-gal, D-galactose; Veh group, vehicle control group; Aging group, D-gal-induced aging group. *p < 0.05, **p < 0.01 compared to the Aging group. ##p < 0.01 compared to the Veh group.
Korean J Physiol Pharmacol 2021;25:131-137
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