The Korean Journal of Physiology & Pharmacology

Table. 1. Table 1

Effect of maternal high fructose exposure on serum biochemical parameters at 28 weeks in male and female offspring

	Control		Fructose		Control		Fructose

	Sham	Orchiectomy	Sham	Orchiectomy	Sham	Ovariectomy	Sham	Ovariectomy
ALT (U/L)	22.2 ± 3.2	55.3 ± 2.1⁺⁺	35.0 ± 5.0^*	73.0 ± 2.8^#	10.5 ± 3.0	20 ± 3.5⁺	20.5 ± 2.0^*	42.5 ± 3.5^#
AST (U/L)	60.0 ± 5.2	101.2 ± 12.2⁺⁺	129.2 ± 20^**	95.0 ± 11.5	40.5 ± 7.2	45.2 ± 10.5	60.2 ± 5.0^*	85.3 ± 3.3^#
Glucose(mg/dl)	72.0 ± 5.6	113.5 ± 10.3⁺	120 ± 8.1^**	133.5 ± 9.5	72.3 ± 8.5	85.2 ± 11.5	115.3 ± 9.2^*	105.2 ± 7.3
Triglyceride(mg/dl)	90.5 ± 20.4	63.2 ± 18.3⁺	141.5 ± 28.0^*	181.0 ± 25.6^#	50.3 ± 12.4	76.0 ± 15.0	118.2 ± 10.3^**	130.3 ± 16.5
Totalcholesterol(mg/dl)	61.8 ± 8.2	95.3 ± 20.2⁺	125.2 ± 25.0^*	125.8 ± 7.5	45.3 ± 8.4	50.0 ± 9.5	131.5 ± 20.1^**	145.8 ± 9.0
Uric acid(mg/dl)	6.8 ± 0.5	6.6 ± 1.2	6.3 ± 1.8	6.5 ± 2.2	6.4 ± 1.0	6.8 ± 2.5	6.6 ± 1.2	6.2 ± 3.5

ALT, alanine aminotransferase; AST, aspartate aminotransferase. Blood was obtained from mice (each group, n = 6) (⁺p < 0.05 and ⁺⁺p < 0.01, control sham vs. control gonadectomy. *p < 0.05 and **p < 0.01, control sham vs. fructose sham. ^#p < 0.05, fructose sham vs. fructose gonadectomy).

Korean J Physiol Pharmacol 2021;25:39-49 https://doi.org/10.4196/kjpp.2021.25.1.39