Fig. 1. Eupatilin restored weight loss in the alcoholic liver disease model. Body weights of rats (n = 7) were measured. Control group: saline + 0.1% CMC-Na, vehicle group: 7 g/kg ethanol + 0.1% CMC-Na, silymarin (positive control) group: 7 g/kg ethanol + silymarin 10 mg/kg, eupatilin 10 mg/kg: 7 g/kg ethanol + eupatilin 10 mg/kg, eupatilin 30 mg/kg: 7 g/kg ethanol + eupatilin 30 mg/kg, and eupatilin 100 mg/kg: 7 g/kg ethanol + eupatilin 100 mg/kg. Data are expressed as mean ± standard error of the mean. CMC-Na, sodium carboxymethyl cellulose; ALD, alcoholic liver disease. ^##p < 0.01 vs. control group, *p < 0.05, **p < 0.01 vs. vehicle group.

Korean J Physiol Pharmacol 2020;24:385-394 https://doi.org/10.4196/kjpp.2020.24.5.385

© Korean J Physiol Pharmacol