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Fig. 4.

Inhibitory effect of α-isocubebene (ICB) on MLC phosphorylation in phenylephrine (PE) (A)- or norepinephrine (NE) (B)-treated VSMC.

After pretreating cells with vehicle or ICB (10 µg/ml), PE (1 µM) or NE (1 µM) was added to elicit MLC phosphorylation. Blots are representative of 5–6 independent experiments. Densitometric results of Western blot are shown in the bottom panel. The p-MLC to t-MLC ratios were presented as the means±SEM of 5–6 independent experiments. **p<0.01 vs. corresponding value in control. ##p<0.01 vs. corresponding value in vehicle.

Korean J Physiol Pharmacol 2018;22:437-445
© Korean J Physiol Pharmacol