Effects of α-isocubebene (ICB) on vascular tension in mouse thoracic aorta pre-contracted with phenylephrine (PE, 1 µM).
In mice thoracic aorta with (ED+) or without (ED−) endothelium, ICB (3–30 µg/ml) was added cumulatively to elicit vasodilation. Tracings are representative of 6 independent experiments (A). Percentage vasodilation represents relative value to vasodilation induced by SNP (0.1 µM). Data was presented as the means±SEM of 6 independent experiments (B).
