Effects of α-isocubebene (ICB) on acetylcholine (Ach)- or sodium nitroprusside (SNP)-induced vasodilation in mouse thoracic aorta pre-contracted with phenylephrine (PE, 1 µM).
Under pretreatment with vehicle or ICB (1–10 µg/ml), Ach (1 µM) or SNP (0.1 µM) was added to elicit vasodilation. Tracings are representative of 5 independent experiments (A). Percentage vasodilation was presented as the means±SEM of 5 independent experiments (B).
