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Fig. 1.

Effects of α-isocubebene (ICB) on phenylephrine (PE)- and norepinephrine (NE)-induced contractions in mouse thoracic aorta.

Under pretreatment with vehicle or ICB (1–10 µg/ml), PE (10−7−3×10−6 M) (A) or NE (10−8−3×10−7 M) (B) was added in a step-wise manner to elicit vasocontraction. Tracings are representative of 4–5 independent experiments. Bottom: percentage vasocontraction represents contraction relative to that elicited by 60 mM KCl. Results were presented as the means±SEM of 4–5 independent experiments. *p<0.05; **p<0.01 vs. corresponding value in Vehicle.

Korean J Physiol Pharmacol 2018;22:437-445
© Korean J Physiol Pharmacol