Adenine suppresses LPS-induced production of pro-inflammatory cytokines in the peritoneal cavity.
BALB/c mice were injected into peritoneum with LPS (1 mg/kg) 1 h after injection of adenine (10 mg/kg) or PBS. Peritoneal lavages were collected 1 h after LPS administration to measure the levels of TNF-α (A) and IL-6 (B). Significant difference against a control group is indicated as *(p<0.05).