Download original image
Fig. 1.

CA protected against APAP-induced liver injury. Male C57BL/6J mice were administered with either CA (100 mg/kg per day) or an equal volume of 0.5% CMC-Na for three days. At day 3, the mice were intraperitoneally injected with either 400 mg/kg APAP or an equal volume of PBS. (A) Representative images of H&E-staining in liver sections harvested at 6 hours post-APAP injection Magnification: 200×. (B, C) The serum levels of both ALT and AST were determined by a commercial kit. Data are shown as means±S.E.M. *p<0.05 versus APAP alone group (n=8).

Korean J Physiol Pharmacol 2016;20:15-23
© Korean J Physiol Pharmacol