Effects of UTD2 on the activity and expression of MMP-2 in MDA-MB-231 cells. (A) MMP2 in MDA-MB-231 cells was determined by zymography; the cells and cell lysates were treated as described in materials and methods. (B) RT-PCR analysis of the mRNA levels of MMP-2 in MDA-MB-231 cells. (C) Actin was used as loading control for the RT-PCR analysis. The data are presented as mean±SE. of these independent experiments (n=4).
