Fig. 2.

Effects of UTD2 on the cell motility of MCF-7 cells. The cells were preincubated with or without the indicated concentrations of UTD2. The cell motility was measured as described in materials and methods. (A) Wound-closure of MCF-7 cells treated with IC₅₀ dose of UTD2 for 24 hours. (B) Wound closure of cells treated with IC₁₀ and IC₅₀ doses of UTD2 for 24 hours as a ratio relative to control cells. (C) Migration of MCF-7 cells treated with IC₁₀ and IC₅₀ concentrations of UTD2 for 16 hours. (D) Migration of the drug treated MCF-7 cells presented as a ratio relative to control cells. (E) Invasion of MCF-7 cells incubated with IC₁₀ and IC₅₀ doses of UTD2 for 16 hours. (F) Invasion of the drug treated MCF-7 cells presented as a ratio relative to control cells. (G) The adhesion of MCF-7 cells incubated with IC₁₀ and IC₅₀ doses of UTD2 for 2 hours relative to control cell adhesion. The data are presented as mean±SE of these independent experiments (n=4), ^**p<0.01.

Korean J Physiol Pharmacol 2014;18:109-120 https://doi.org/10.4196/kjpp.2014.18.2.109

© Korean J Physiol Pharmacol