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Fig. 4.

Effects of compound 4 on LPS-induced inflammatory cytokine production in murine macrophages. RAW264.7 cells were treated with 0~10 µM of compound 4 in the presence of 100 ng/ml LPS or with LPS alone for 24 h. The cell culture media were then collected, and the amount of (A) IL-1β and (B) IL-6 released was measured. The results are reported as mean±SEM of three independent experiments in triplicate. Statistical significance is based on the difference when compared with LPS-stimulated cells (**p<0.01, ***p<0.001).

Korean J Physiol Pharmacol 2013;17:217-222
© Korean J Physiol Pharmacol