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• Luteolin inhibits H₂O₂-induced cellular senescence via modulation of SIRT1 and p53

  Ri Zhe Zhu^#, Bing Si Li^#, Shang Shang Gao, Jae Ho Seo^*, and Byung-Min Choi^*

  2021; 25(4): 297-305
  https://doi.org/10.4196/kjpp.2021.25.4.297

• Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling pathway

  Zhi-Qing Chen¹, You Zhou¹, Jun-Wen Huang¹, Feng Chen², Jing Zheng¹, Hao-Liang Li¹, Tao Li¹, and Lang Li^1,*

  2021; 25(2): 147-157
  https://doi.org/10.4196/kjpp.2021.25.2.147

• Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-κB pathway

  Hualei Bai¹, Shize Chen¹, Tiezheng Yuan¹, Dongyuan Xu¹, Songbiao Cui^2,*, and Xiangdan Li^1,*

  2021; 25(3): 217-225
  https://doi.org/10.4196/kjpp.2021.25.3.217

• Flos magnoliae constituent fargesin has an anti-allergic effect via ORAI1 channel inhibition

  Phan Thi Lam Hong^1,2,#, Hyun Jong Kim^2,#, Woo Kyung Kim^2,3,*, and Joo Hyun Nam^1,2,*

  2021; 25(3): 251-258
  https://doi.org/10.4196/kjpp.2021.25.3.251

• Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway

  Haixia Wang^1,2, Xin Shi², Longlong Cheng³, Jie Han², and Jianjun Mu^1,*

  2021; 25(3): 239-249
  https://doi.org/10.4196/kjpp.2021.25.3.239

• Gamma-aminobutyric acid-salt attenuated high cholesterol/high salt diet induced hypertension in mice

  Myeongjoo Son^1,2,#, Seyeon Oh^2,#, Hye Sun Lee², Junwon Choi^1,2, Bae-Jin Lee³, Joung-Hyun Park³, Chul Hyun Park⁴, Kuk Hui Son^4,*, and Kyunghee Byun^1,2,*

  2021; 25(1): 27-38
  https://doi.org/10.4196/kjpp.2021.25.1.27

• Apoptin gene delivery by a PAMAM dendrimer modified with a nuclear localization signal peptide as a gene carrier for brain cancer therapy

  Yoonhee Bae^1,2, Jell Lee³, Changwon Kho², Joon Sig Choi³, and Jin Han^1,*

  2021; 25(5): 467-478
  https://doi.org/10.4196/kjpp.2021.25.5.467

• Protective effects of lutein against vancomycin-induced acute renal injury in mice via upregulation of peroxisome proliferator-activated receptor gamma/nuclear factor erythroid 2-related factor 2 and inhibition nuclear factor-kappaB/caspase 3

  Promise M. Emeka^1,*, Sahibzada T. Rasool², Mohamed A. Morsy^1,3, Mohamed I. Hairul Islam⁴, and Muhammad S. Chohan²

  2021; 25(4): 321-331
  https://doi.org/10.4196/kjpp.2021.25.4.321

• Carbon monoxide activates large-conductance calcium-activated potassium channels of human cardiac fibroblasts through various mechanisms

  Hyemi Bae¹, Taeho Kim², and Inja Lim^1,*

  2021; 25(3): 227-237
  https://doi.org/10.4196/kjpp.2021.25.3.227

• Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging rats by inhibiting TGF-β/p38/MK2 signaling pathway

  Jing Cheng¹, Chaoyang Ren², Renli Cheng³, Yunning Li⁴, Ping Liu¹, Wei Wang^1,*, and Li Liu^1,*

  2021; 25(2): 131-137
  https://doi.org/10.4196/kjpp.2021.25.2.131