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Fig. 3. Effects of mangiferin on cardiac oxidative stress (A) and inflammation (B) in D-gal-induced aging rats. The activities of enzymatic antioxidants SOD and CAT, as well as the level of lipid peroxidation marker MDA and proinflammatory cytokines IL-1β, IL-6 and TNF-α were measured in accordance with the instructions of commercial kits. Values (n = 8) were presented as mean ± standard deviation. D-gal, D-galactose; SOD, superoxide dismutase; CAT, catalase; MDA, malondialdehyde; IL, interleukin; TNF, tumor necrosis factor; Veh group, vehicle control group; Aging group, D-gal-induced aging group. **p < 0.01 compared to the Aging group. ##p < 0.01 compared to the Veh group.
Korean J Physiol Pharmacol 2021;25:131~137 https://doi.org/10.4196/kjpp.2021.25.2.131
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