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Fig. 5. Centromere protein U (CENPU) promoted bladder cancer development in vivo by elevating mitochondrial ribosomal protein s28 (MRPS28) expression. (A) Picture of tumor tissues and volume of tumors from nude mice in each group from 1–4 weeks. (B, C) Immunohistochemistry and Western blot analysis was used to measure the expression of CENPU and MRPS28 proteins in tumor tissues of nude mice. (D) Western blot analysis to measure N-cadherin, Slug and Snail protein expression in tumor tissues. In this study, T24 cells were injected subcutaneously into the back of nude mice. *p < 0.05 or ***p < 0.001 vs. pcDNA-NC group. #p < 0.05 or ##p < 0.01 or ###p < 0.001 vs. pcDNA-CENPU group.
Korean J Physiol Pharmacol 2021;25:119~129 https://doi.org/10.4196/kjpp.2021.25.2.119
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