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Fig. 6. Paeoniflorin reduced microglial activation. Paeoniflorin reduced Iba-1 expression (A) microglial activation TLR4 (B) and also reduced microglial activation HIF-1α (C). Values are represented as mean ± standard deviation, n = 6. p < 0.05 as determined by one-way ANOVA followed by DMRT analysis. Iba-1, ionized calcium binding adaptor molecule 1; HIF-1α, hypoxia-inducible factor-1 alpha; H/I, hypoxia/ischemia; P, postpartum day. *Represents p < 0.05 vs. control; #represents p < 0.05 vs. H/I control. a-eRepresents mean values from different experimental groups that differ from each other at p < 0.05.
Korean J Physiol Pharmacol 2021;25:97~109 https://doi.org/10.4196/kjpp.2021.25.2.97
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